INDICATIONS AND USAGE:
Duloxetine delayed-release capsules are used for treating depression and generalized anxiety disorder. It is used for managing chronic musculoskeletal pain, including osteoarthritis and chronic low back pain
MECHANISM OF ACTION:
Duloxetine inhibits the reuptake of serotonin and norepinephrine (NE) in the central nervous system. Duloxetine increases dopamine (DA) specifically in the prefrontal cortex, where there are few DA reuptake pumps, via the inhibition of NE reuptake pumps (NET) which is believed to mediate reuptake of DA and NE.
Additional Information
| Percentage | 17%, 20% |
|---|---|
| Quality Standard | USP43 |
| Documentation Available: | Complete Technical Package |
| Release Type | Delayed Release |
| Forms of PFI | Pellets/Micro pellets (for capsules) |
| Target Formulations | Capsules |
