FDF Products

Brinzolamide Eye Drop – (Nano suspension 1% w/v)

The Nano emulsion developed by Murli Krishna Pharma ensures the following:

• Nano particle based matrix, which can deliver hydrophilic as well as hydrophobic drugs using a combination of hydrophilic and hydrophobic excipients as a clear solution. This cogent use of excipients ensures that the drug is absorbed optimally and the Nano particles ensure that the drug penetrates not only through the hydrophobic and hydrophilic channels but also through the OraSerrata, which protects the eye from any foreign body entering the optical cavity.
• The protein binding is minimized due to encapsulation.
• The particle size is to the tune of 100 nm which makes the product easily sterile filterable.
• The formulation is in form of a clear solution and is available in the same concentration as the innovator i.e. 10 mg/ml. The product can be offered as a solution that can be sterile filtered and filled.
• We offer development services in case of a requirement for different formulation/dosage/strength
• Offer complete technical package for registrations in all regulated/semi regulated markets
• Products protected by ongoing Patents are not offered by MKPPL.

Budesonide Soft Mist Inhaler, 100mg

MK-VitFe – Transdermal Liposomal Lotion for Topical Massage

Product contains API of Ferrous Bisglycinate (Elemental Iron), Vitamin B12, Vitamin D3, Folic acid

Benefits of Transdermal Liposomal Lotion:

• Easy for application
• Skin friendly, Non-irritant
• Bypass first pass effect
• Liposomal based formulation possesses advantage over conventional lotion, due to very small particle size they can easily penetrate through the skin uppermost layer.
• Convenient for unconscious patients or patients to have difficulty in oral administration.

Paclitaxel (protein-bound particles) for Injectable Suspension

• Nab Paclitaxel is a ground-breaking chemotherapy medication.
• It is uniquely formulated as an albumin-bound nanoparticle, which enhances both its efficacy and safety.
• Nab Paclitaxel is utilized in the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
• Administration is typically via intravenous infusion.

Revolutionizing Cancer Care with Nab Paclitaxel Treatment

Advantages of Nab Paclitaxel:

• Enhanced Solubility: The nanoparticle form of Nab Paclitaxel improves its solubility in water, facilitating easier administration.
• Targeted Delivery: Nano-sized particles exhibit a preference for accumulating at tumor sites, boosting the drug’s effectiveness.
• Reduced Side Effects: Nab Paclitaxel nanoparticles evade recognition by healthy tissues, thereby minimizing adverse
  effects.
• Higher Dosing: This enables the use of higher maximum tolerated doses (MTD).
• Improved Pharmacokinetics: Longer half-life and superior tumor accumulation.

The Significance of Encapsulation:

• Encapsulation of paclitaxel is crucial for precise targeting while minimizing side effects.
• Conventional systemic administration affects healthy cells throughout the body.
• Encapsulation guarantees that the drug efficiently reaches the tumor site.